A basic course in biochemistry that includes fundamental organic chemistry, biological information transfer processes, energy conservation metabolism, and special topics such as membrane transport and the biochemistry of vision. Intended for nurses and allied health professionals; open to others with permission of instructor. Lecture and discussion. Course Director: Dr. Jeanne Stuckey

For undergraduates who are in the Biochemistry Concentration Program. Prerequisites: BIOLCHEM 451/452 and permission of instructor. Course Directors: Dr. David Turner, Dr. Alex Ninfa, and Dr. Michael Uhler.

A one-term introductory biochemistry course that covers the biochemistry of the living state, the chemistry of amino acids, proteins, nucleic acids, carbohydrates, lipids, and steroids, energy transformations and chemical reactions in living cells, function of immune system and action of hormones, and self-regulation and self-replication of living organisms. Prerequisites: two semesters of organic chemistry. No credit is granted to students who have completed Biology 310 or 311 or Biochemistry 451/452.
Course Directors: Dr. Jerry Menon (Fall), Dr. Ray Trievel (Winter)

A rigorous introduction to biochemistry with a chemical emphasis. Designed for undergraduates in the “Biochemistry Concentration Program” but open to graduate students with a strong background in chemistry. Prerequisites: Chem 215, Biol. 152 or 195, and Math 115. No credit granted to those who have completed or are enrolled in Biol. 310 or 311 or Biol. Chem. 415. Lecture.
Course Directors: Dr. Charles Yocum, Dr. Katrin Karbstein

A continuation of Biochemistry 451 which is a prerequisite. Course Director: Dr. Alex Ninfa.
Course Website

This course will provide a high-level overview on the structure, function and chemistry of biological macromolecules including proteins, nucleic acids and carbohydrates. Topics include protein and nucleic acid folding, energetics of macromolecular interactions (kinetics and thermodynamics), and mechanistic enzymology. Using specific examples from the current literature, each topic will stress how chemists have used molecular level tools and probes to help understand the specific systems under study. The over arching theme in this course will be that structure and function are intimately linked.
Prerequisites: None. Course Faculty: Dr. Nils Walter, Dr. Janet Smith, Dr. Steve Ragsdale.

This course is a continuation of Chemical Biology 501. The basic concepts obtained in Chemical Biology 501 will be applied to and demonstrated in three broad areas of interest to both chemists and biologists. The first topic will discuss combinatorial methods including SELEX and gene shuffling, combinatorial organic synthesis, high throughput screening and chemical genetics. The second topic will focus on signal transduction, emphasizing general concepts (at the molecular level) and how small molecules have been used to probe and modulate signal transduction pathways. The final topic will cover protein translation, stressing mechanistic aspects of protein synthesis and folding in vivo.
Prerequisites: BIOLCHEM 501 (Chemical Biology I) is recommended.
Course Director: Dr. Jason Gestwicki

This course will provide a high-level overview on the structure, function and biology of nucleic acids. After gaining a high-level background in nucleic acid structure and their interactions with proteins, we will study important RNA-based biological processes, including pre-mRNA splicing, translation, RNAI and RNA decay. Lecture. Prerequisites: Undergraduates must have taken Chem/Biochem 451, Chem 452.
Course Director: Dr. Katrin Karbstein

A one-term introductory biochemistry course that covers the biochemistry of the living state, the chemistry of amino acids, proteins, nucleic acids, carbohydrates, lipids, and steroids, energy transformations and chemical reactions in living cells, function of immune system and action of hormones, and self-regulation and self-replication of living organisms.
Prerequisites: two semesters of organic chemistry. No credit is granted to students who have completed or are enrolled in Biology 310 or 311 or Biochemistry 451/452. Lecture.
Course Directors: Dr. Jerry Menon (Fall), Dr. Ray Trievel (Winter)

This graduate course is designed to present basic information as well as the most recent developments in key areas of cell biology, including membranes, protein synthesis, folding and trafficking, epithelial polarity, cytoskeleton, cell-cell and cell-substrate interactions, and signal transduction. Participating faculty are drawn from various campus and medical school departments and provide lectures in areas of their expertise. Lecturers are encouraged to provide a part of the lecture material in the context of actual experiments so that students are exposed to current experimental approaches in cell biology, as well as basic information. In addition to a highly recommended cell biology textbook, reading lists are provided, and 1-2 papers are generally put on reserve in the library for each lecture. Students will be expected to demonstrate their knowledge of course material by examinations. Course Director: Dr. Stephen A. Ernst.